Scazol forte

Each f/c tablet contains : Secnidazole 1000mg.
Scazol Forte (Secnidazole) is a 5-nitroimidazole derivative with activity against several protozoa including
Entamoeba histolytica, Giardia Lamblia and trichomonas vaginalis. After single oral dose of 2 gm the maximum
concentration in serum occurs within 3 hours. The plasma elimination half life is about 20 hours. Secnidazole is
mainly eliminated in the urine (50% of the ingested dose is excreted within 25 hours). It crosses the placenta and
can be found in breast milk.
Scazol Forte is indicated for treatment the following cases :-
- Intestinal amoebiasis. - Hepatic amoebiasis.
- Giardiasis. - Urogenital trichomoniasis in both males and females.
- Anaerobic septicaemias and nonspecific vaginitis.
Scazol Forte should be taken before a meal.
- Intestinal amoebiasis
• Acute symptomatic amoebiasis (histolytic form)
Adults : 2 gm in one single dose for one day.
Children : 30 mg / kg / day in one single dose for one day.
• Asymptomatic amoebiasis (minute and cystic forms)
Adults : 2 gm as a single dose per day for 3 days.
Children : 30 mg / kg / day for 3 days.
- Hepatic amoebiasis
Adult : 1.5 gm per day in single or divided doses for 5 days.
Children : 30 mg / kg / day in single or divided doses for 5 days.
- Trichomoniasis, Giardiasis and Bacterial vaginosis : Single dose of 2 gm for one day.
- Hypersensitivity to imidazole derivatives.
- It is contraindicated in patients who suffer from organic neurological disorders and blood dyscrasias.
- If various neurological signs develop while using the drug stop it immediately.
- Avoid alcohol consumption.
Use in Pregnancy and lactation
Secnidazole should be avoided during pregnancy and lactation.
- Secnidazole has been reported to potentiate the effect of warfarin. Hence prothrombin levels should be checked
frequently, the dose of anticoagulants should be adjusted during treatment with Secnidazole.
- Concomitant administration of Secnidazole and disulfiram may cause delirium and confusion.
- The most frequently occurring side effects are nausea, sometimes accompanied by headache, anorexia and
occasionally diarrhoea, epigastric distress and metallic taste.
- Rarely occur hypersensitivity reactions including urticaria, pruritis and oedema.
- Leucopenia which is reversible upon stopping the treatment.
- Tiredness, furred tongue, darkening of the urine.
Store below 25°C in a dry place.
Scazol Forte: Blister Pack of 2 tablets and hospital packs of different sizes
Scazol Forte