Each sustained release capsule contains :
Dried Ferrous sulphate B.P. 150.0 mg
|Zinc sulphate B.P. equivalent to zinc sulphate monohydrate
Fefosan Z contains iron (in ferrous form). Iron is an essential constituent of hemoglobin which is vital for
normal erythropoiesis and oxygen transport capacity of the blood. It is also involved in myoglobin synthesis
and serves as a cofactor for many heme and non-heme-Iron dependent enzymes. Folic acid is required for
nucleoprotein synthesis and maintenance of normal erythropoiesis. Folic acid stimulates production of red
and white blood cells and platelets in certain megaloplastic anemia. Fefosan Z also contains zinc which is
essential for many physiological and biological process including normal bone growth, immune function,
insulin storage, sexual maturation, wound healing, tissue repair and taste accuracy.
Fefosan Z is indicated in the cases of nutritional iron deficiency and in any other causes in which iron
deficiency can occur as pregnancy,lactation, children, in patients who are taking NSAIDs for long period and
patients with chronic inflammatory diseases.
DOSAGE AND ADMINISTRATION :
The recommended dose is 1 - 2 capsules daily or as recommended by the physician.
RESTRICTIONS ON USE :
Patients with hypersensitivity to any ingredients or those with iron overload.
- Ferrous sulphate should be taken with care in patients who may develop iron overload such as those with
haemochromatosis, haemolytic anaemia or red cell aplasia.
- Fefosan Z should not be used during the first trimester of pregnancy.
DRUG INTERACTIONS :
- Absorption of both iron and tetracyclines is diminished when they are taken concomitantly by mouth.
- Iron absorption may be impaired by concomitant adminstration of antacid or penicillamine. Such potential
interactions can be reduced by separating administration of each product by several hours .
ADVERSE EFFECTS :
Commonly seen adverse effects are nausea, discomfort, diarrhea or constipation and black stools.
Iron overdosage is dangerous, particularly in children, and requires immediate attention. Treatment is
necessary if more than 30 mg elemental iron per kilogram of body weight has been ingested. symptoms may
include abdominal pain, vomiting, diarrhea and haematemesis, within more severe cases, coma, convulsions
and shock. Acute renal failure and acute hepatic necrosis may develop. Gastric lavage should be carried out
in early stages, or if this is not possible, vomiting should be induced.Give oral desferrioxamine
(2 g for children or 5 g for adults) and demulcents. If serum iron levels at 4 hours or more post-ingestion are
over 5 mg / L in children or 8 mg /L in adults, or if the patient is in shock or coma, intramuscular or
intravenous desferrioxamine should be used according to instructions for this product. Symptomatic and
supportive measures should be given as required.
STORAGE INSTRUCTIONS :
Store below 30°C, in a dry place . Protect from light.
Fefosan Z Capsule : Pack of 20 capsules and hospital packs of different sizes.