Each 5 ml (reconstituted suspension) contains : Erythromycin Ethyl Succinate equivalent to Erythromycin 125 mg,

200 mg or 250 mg .

Each f/c tablet contains : Erythromycin Stearate equivalent to Erythromycin 250 mg or 500 mg .


Erythrosan (Erythromycin) is a macrolide antibiotic with a primarily bacteriostatic action against a broad range of

bacteria including Gram - positive bacteria such as Streptococcus pneumoniae, Streptococcus pyogenes and most

strains of Staphylococcus aureus, Bacillus anthracis, Corynebacterium diphtheriae and Clostridium spp., Gram -

negative bacteria such as Neisseria, Moraxella, H. influenzae, Actinomyces, Chlamydia, Rickettsias, Treponema

pallidum .Erythromycin is adequately absorbed after oral administration. Peak plasma concentrations occur between

1 and 4 hours. Erythromycin is widely distributed throughout body tissues and fluids with a high concentration in the

liver and spleen. It is mainly excreted in the bile. Erythromycin crosses the placenta and is excreted in breast milk.


Erythrosan is indicated in the treatment of infections caused by susceptible microorganisms as :

- Eye infections : blepharitis.

- Ear infections : otitis media, otitis externa, mastoiditis.

- Oral infections : gingivitis, Vincent’s angina, dental infections.

- Respiratory tract infections : tonsillitis , pharyngitis, laryngitis, sinusitis, secondary infections in colds and influenza ,

tracheitis , acute and chronic bronchitis, pneumonia (including Mycoplasma pneumonia).

- Gastro-intestinal tract infections : cholecystitis, staphylococcus enterocolitis, intestinal amebiasis (Entamoeba


- Skin and soft tissue infections : boils , abscesses, pustular acne , impetigo.

- Prophylaxis : pre and post-operative , trauma , burns , rheumatic fever.

- Other infections : diphtheria, scarlet fever, urethritis, gonorrhea, syphilis and lymphogranuloma venerum.


Children up to 2 years : 125 mg every 6 hours.

Children 2 - 8 years : 200 - 250 mg every 6 hours and may be doubled for severe infections.

Adults and children over 8 years : 250 - 500 mg every 6 hours or 0.5 - 1 g every 12 hours and up to 4 g daily in

severe infections.

Early syphilis : 500 mg 4 times daily for 14 - 21 days.

Non-gonococcal urethritis : 500 mg 2 - 4 times daily for 7 - 14 days.



- Erythromycin is contraindicated in patients with known hypersensitivity to the drug.

- Erythromycin is contraindicated in patients taking terfenadine.


- As with other Erythromycins caution should be exercised in patients with existing liver diseases or impaired hepatic


- Use with care in patients with a history of arrhythmias.

Use in pregnancy and lactation

Use erythromycin in pregnant women only if clearly needed and exercise caution when administer to nursing women.


Concomitant administration of Erythromycin with the following drugs may increase the potentiality or the toxicity of

these drugs because of its effect on the cytochrome P - 450 : Alfentanil, Astemizole, Bromocriptine, Theophylline,

Digoxin, Warfarin, Ergotamine, Triazolam, and Terfenadine.


The most frequent side effects are nausea, vomiting, abdominal discomfort, diarrhea, urticaria, rashes, and allergic



Dry powder : Store below 30oC in a dry place.

Reconstituted suspension : Store in a refrigerator and use within 10 days.

Tablet : Store below 30oC in a dry place.


Erythrosan Powder for oral suspension 125, 200 or 250 mg : Bottle of 100 ml (after reconstitution).

Erythrosan f/c Tablets : Pack of 20 tablets and hospital packs of different sizes.