COMPOSITION :

Each 5 ml (teaspoonful) contains :

Chlorpheniramine Maleate 4 mg

Dextromethorphane Hydrobromide 6.25 mg

Ephedrine Hydrochloride 7.5 mg

Guaiphenesin 50 mg.

DESCRIPTION :

Tussimax syrup is an effective formula that contains four active ingredients including Chlorpheniramine that is an

antihistaminic agent . Dextromethorphane acts centrally to reduce cough with no depression of the central nervous system.

Ephedrine has sympathomimetic effect which causes relaxation of bronchospasm hence breathing becomes more convenient.

Guaiphenesin has a mild expectorant effect by reducing viscosity of tenacious secretions .

INDICATIONS :

- Acute and chronic bronchitis.

- Common cold accompanied by cough.

- As adjuvant in asthmatic patients, due to the relaxant effect of bronchi.

DOSAGE & ADMINISTRATION :

Tussimax syrup is administered two - four times daily as follows :

Adults : 10 ml

Children : 5 ml

RESTRICTIONS ON USE :

Contraindications

- Hypersensitivity to the ingredients .

- In patients who are taking or have taken monoamine oxidase inhibitors (MAOIs) for the last two weeks.

Precuations

- Patients should be warned about possible additive effects with alcohol and central nervous system depressants .

- Given with caution to elderly and patients with diabetes mellitus , hyperthyroidism, prostatic hypertrophy, cardiovascular

disorders, hypertension ,arrhythmia or patients taking sympathomimetics agents .

Effect on the ability to drive vehicles or use machines

Administer with caution since it may cause drowsiness .

Use in pregnancy & lactation

There are no studies on animals or humans, so Tussimax should not be used during pregnancy or lactation unless prescribed

by physician.

DRUG INTERACTIONS :

- Concomitant administration with alcohol or sedative drugs will potentiate the sedative effects of Chlorpheniramine maleate.

- Concomitant administration with (MAOI) leads to increase blood pressure.

- Concomitant administration with sympathomimetics agents or theophylline leads to increase cardiac stimulation .

SIDE EFFECTS :

Some mild and transient side effects may occur such as drowsiness, headache, fatigue , blurred vision , nausea, vomiting

anorexia ,dry mouth ,gastrointestinal disturbances .

STORAGE INSTRUCTIONS :

Store below 30°C, protect from light.

PRESENTATIONS :

Tussimax syrup : Bottle of 100 ml .