O.M. Strip


Each capsule contains : Omeprazole 20 mg (As enteric coated pellets) .


O.M. Strip is a proton pump inhibitor. It inhibits the secretion of gastric acid by irreversibly blocking the enzyme

system of H+ / K+- ATPase (the proton pump) in the parietal cells . It inhibits both basal and stimulated acid

secretion irrespective of the stimulus. Omeprazole is rapidly absorbed and its absorption is not affected by food.

It is almost completely metabolized in the liver and rapidly eliminated mostly in the urine .The elimination half life

is about 0.5 to 3 hrs. Omeprazole is highly bound by 95% to plasma proteins.


O.M. Strip is indicated in the treatment of :

- Gastro-oesophageal reflux disease.

- Gastric ulcer .

- Duodenal ulcer.

- Zollinger Ellison syndrome.

- Reflux oesophagitis.


- Gastro-oesophageal reflux disease : 20 to 40 mg once daily for 4 to 12 weeks.

Maintenance therapy : 20 mg once daily .

- Gastric ulcer : 20 mg once daily for 8 weeks.

For the prevention of relapse a maintenance dose of 10 - 20 mg once daily is recommended .

- Duodenal ulcer : 20 mg once daily for 4 weeks.

For the prevention of relapse a maintenance dose of 10 - 20 mg once daily is recommended.

- Zollinger-Ellison syndrome : Long term management requires administration of 60 mg up to 120 mg daily of

O.M. Strip in divided doses. In some cases it may require more than 120 mg daily given in 2 or 3 divided doses.

- Reflux oesophagitis : 20 mg once daily for 4 - 8 weeks.

- Helicobacter Pylori associated with peptic ulcer disease : 40 - 80 mg daily with Amoxicillin 1.5 gm daily in

divided doses for 2 weeks .



Hypersensitivity to Omeprazole .

Use in pregnancy and lactation

It is not recommended unless prescribed by the physician.


Treatment with Omeprazole may mask symptoms of malignancy and therefore delay diagnosis .


- Omeprazole can prolong the elimination of Diazepam , Warfarin and Phenytoin.

- It may increase absorption of Digoxin and decrease the effectiveness of Prednisone.

- Omeprazole inhibits the activity of some hepatic cytochrome P- 450 enzymes.


O.M. Strip is well tolerated.The most common adverse effects are diarrhoea, skin rash and headache which are

mild and transient. The rare adverse effects include arthralgia, myalgia and blood disturbances.


- Store below 30°C, protect from light and humidity .


O.M. Strip : Pack of 10×10 capsules .