Section :
Bisol
COMPOSITION :
Each 5 ml contains : Bromhexine Hydrochloride 4 mg.
Each tablet contains : Bromhexine Hydrochloride 4 mg , 8 mg.
DESCRIPTION :
Bisol (Bromhexine Hydrochloride) is a systemic mucolytic agent. Bisol is rapidly absorbed from the GIT. The
increase in sputum production becomes evident after 2 - 3 days following initiation of therapy. The breakdown of
acid mucopolysaccharide fibers makes the sputum thinner and less viscid and therefore more easily removed by
coughing. Although sputum volume eventually decreases, its viscosity remains low for as long as treatment with
Bisol is maintained.
INDICATIONS :
Bisol is indicated for the treatment of respiratory disorders associated with viscid or excessive mucoid secretions
such as : Asthma, bronchitis, emphysema, pneumoconiosis, chronic inflammatory pulmonary conditions,
bronchiectasis and all forms of tracheobronchitis.
During acute exacerbations of bronchitis Bisol should be given with the appropriate antibiotic.
DOSAGE AND ADMINISTRATION :
RESTRICTIONS ON USE :
Contraindications
Not documented.
Precautions
Patients being treated with Bisol should be warned to expect an increase in the flow of secretions.
Effects on the capacity to drive vehicles or use machines
Bisol does not interfere with activities requiring mental alertness.
Use in Pregnancy and Lactation
Administer under medical supervision.
DRUG INTERACTIONS :
Not documented.
SIDE EFFECTS :
Occasional gastro-intestinal side effects may occur, but these are almost invariably mild.
STORAGE INSTRUCTIONS :
Syrup : Store below 30oC. Protect from light .
Tablet : Store below 30oC, in a dry place. Protect from light .
PRESENTATION :
Bisol Syrup : Bottles of 100 ml.
Bisol 4 Tablet : Pack of 20 tablets and hospital packs of different sizes .
Bisol 8 Tablet : Pack of 20 tablets and hospital packs of different sizes .
10 ml syrup or 1 tablet (8 mg) or 2 tablets (4 mg)
5 ml syrup or 1 tablet (4 mg)
2.5 ml syrup
1.25 ml syrup
Adults & Children over 10 years
Children 5-10 years
Children 2-5 years
Children under 2 years
Age Dose (three times daily)