📌 COMPOSITION

• Each 5 ml (teaspoonful) syrup contains: Ambroxol HCl 15 mg.
• Each tablet contains: Ambroxol HCl 30 mg.

📌 DESCRIPTION

Ambrox (Ambroxol HCl) contains Ambroxol, which is the active metabolite of bromhexine, and it is a systemic mucolytic agent. It acts by altering the structure of mucus to decrease its viscosity. It increases respiratory tract secretion and stimulates ciliary movement; therefore, it facilitates expectoration and reduces cough. This results in considerable improvement in breathing. Absorption of Ambroxol hydrochloride is rapid and complete, and maximum plasma levels are reached within 1-2.5 hours following oral administration. It is primarily metabolised in the liver, and the elimination half‑life is approximately 10 hours.

📌 INDICATIONS

Ambrox is indicated to facilitate the expectoration of mucus associated with acute and chronic respiratory tract disorders in the following cases:

• Chronic bronchitis and bronchial asthma.
• Laryngitis, pharyngitis, sinusitis and rhinitis.
• Common cold infections and productive cough.
• Removal of mucous secretions pre‑ and post‑operation.
• Useful in the treatment of respiratory tract infections when used with some antibiotics.

📌 DOSAGE & ADMINISTRATION

Ambrox is administered with meals as follows:

* For the treatment of acute respiratory tract disorders and for the initial treatment of chronic conditions up to 14 days, the dose may be increased to 20 ml of syrup twice daily.

📌 RESTRICTIONS ON USE

Contraindications

Hypersensitivity to Ambroxol.

Precautions

Patients being treated with Ambrox should be warned to expect an increase in the flow of secretions.

Effects on the ability to drive vehicles or use machines

Ambrox does not affect activities requiring mental alertness.

Use in Pregnancy & Lactation

The use of Ambrox is not recommended in pregnant women, especially during the first trimester. Ambrox is excreted in breast milk, so it is not recommended for use in nursing mothers.

📌 DRUG INTERACTIONS

Administration of Ambroxol with antibiotics (amoxicillin, cefuroxime, erythromycin, doxycycline) leads to higher antibiotic concentrations in lung tissue.

📌 SIDE EFFECTS

• Mild gastrointestinal disorders.
• Rare allergic reactions have been reported, such as skin rash.

📌 STORAGE INSTRUCTIONS

• Syrup: Store below 30°C. Protect from light.
• Tablets: Store below 30°C in a dry place. Protect from light.

📌 PHARMACEUTICAL FORMS

• Ambrox syrup: Bottle of 100 ml.
• Ambrox tablets: Packs of different sizes.